Apri Score Calculator. If you're interested in hepatology or liver disease, this i

If you're interested in hepatology or liver disease, this is a must-watch. 50 as the cut-off value for APRI score which was used in some previous prognostic studies (23, 39), patients were also divided into the normal APRI group (score ≤1. Assess likelihood of fibrosis or cirrhosis non-invasively using AST and platelet count. What are the alternatives to APRI? Alternatives to APRI include FIB-4 and ELF, each with their own pros and cons. Are you interested in other calculators that can help assess whether or not a patient has liver disease? Check out the MELD Jul 6, 2025 · What is the APRI Score? The APRI (AST to Platelet Ratio Index) is a simple, non-invasive scoring system used to estimate the degree of liver fibrosis in patients with chronic liver disease, most notably chronic hepatitis C. in 2003, 6 namely, [ (AST of the sample/ reference AST) x 100] / platelets - 3. These hormones are synthetic versions of the naturally occurring female hormones estrogen and progestin. We would really appreciate your feedback to make this page better. Enter laboratory data to calculate the APRI score and evaluate liver health. With just a few clicks, users can access a wide range of online calculators that can perform calculations in a variety of fields, including finance, physics, chemistry, and engineering Download Table | Accuracy of platelet count, AST/ALT ratio, and APri score in predicting advanced fibrosis. It will appear in the oval on the far right (highlighted in yellow). The APRI score holds significant importance in liver-related conditions as it helps healthcare providers: 1. Always consult with hepatologists and gastroenterologists for proper liver disease assessment and management. This AST to platelet ratio index (APRI) calculator helps with cirrhosis diagnosis based on the platelet count and AST level. 0 suggests cirrhosis. The APRI score can help determine the fibrosis stage in liver-related conditions. The APRI (AST to Platelet Ratio Index) score is used to assess liver fibrosis severity. Check FIB 4 Formula & Normal Range. Most laboratories use 40 IU/L as the value for the AST upper limit of normal. 50) and the high The AST to Platelet Ratio Index (APRI score) is an easy-to-use score to predict liver fibrosis18, such as other noninvasive serum markers (FIB-4 index, FLI, NFS, BARD, Forns index19). Common cutoffs (esp. Create, share, and discover interactive calculators for any purpose. 5 into the normal APRI group and an APRI score > 1. 5 low likelihood of significant fibrosis; 0. APRI score should be recorded in results entry in the EHR. Il est également moins informatif pour l'évaluation des stades de fibrose légère. For education only — not medical advice. For fibrosis assessment, scores like FIB-4 or APRI are used. The AST to Platelet Ratio Index (APRI) predicts fibrosis and cirrhosis in hepatitis C patients. The APRI score is not sufficiently sensitive to rule out significant disease, especially with mid-range values. Jun 12, 2025 · Enter AST, ULN, and platelets; the score updates automatically. Ask for a copy of blood test results which are required for use with these calculators. Oct 3, 2024 · The APRI score calculator simplifies the process of estimating liver fibrosis severity, making it a valuable tool in clinical practice for managing patients with chronic liver diseases. The formula is: APRI = (AST level / Upper limit of normal AST) * 100 / Platelet count (10^9/L) The APRI score is then used to estimate the fibrosis stage in liver-related conditions. Free online tool for medical professionals. FIB-4 is the most used, so let’s do a deep dive into its origins… APRI and Fib-4 scores are reasonable tools to allocate NAFLD patients with advanced fibrosis. We decided to add the functionality of the APRI calculator, so you can get a more complete assessment for your liver's condition. Download scientific diagram | Interpretation of APRI, NAFLD Fibrosis Score, BARD Score, and Fib-4 Index from publication: Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Oct 3, 2024 · A pontuação APRI pode substituir a biópsia de fígado? Embora a pontuação APRI ofereça informações valiosas sobre a fibrose hepática, ela não pode substituir totalmente a biópsia de fígado em todos os casos. It calculates a score based on the AST (Aspartate Aminotransferase) level and platelet count from a blood test. Apri is primarily used as a method of birth control to prevent pregnancy by inhibiting ovulation (the release of eggs from the ovaries), altering the cervical UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, Nephrology and Hypertension, Neurology, Obstetrics, Gynecology, and Women Calculate APRI (AST to Platelet Ratio Index) to assess liver fibrosis risk in chronic liver disease. 1: APRI Calculator The Aspartate Aminotransferase to Platelet Ratio Index (APRI) test is a valuable, non-invasive tool used to assess liver fibrosis and potential cirrhosis, particularly in patients with hepatitis C. from publication: Validation of three noninvasive laboratory variables to predict The APRI (AST to Platelet Ratio Index) score is an essential non-invasive tool for assessing liver fibrosis severity. One hundred twenty-three patients who underwent liver biopsy due to chronic hepatitis B were included in the study. Unlike liver biopsies, this method avoids APRI What it measures: fibrosis Who should take it: anyone concerned about their liver Where to get it: primary care provider, online calculator AST to Platelet Ratio Index (APRI) is a blood-based liver test based on the amount of aspartate aminotransferase (AST) and platelets in a person’s body. APRI, FIB-4, and FIB-5 scores of patients who underwent liver biopsy due to CHB were calculated by means of calculators and recorded to be compared with liver biopsies in terms of fibrosis scoring. There are several risk scores out you may have heard about such as FIB-4 (Fibrosis-4), APRI (AST to platelet ratio index), and NFS (NAFLD fibrosis score). Most experts recommend using 40 IU/L as the value for the AST upper limit of normal when calculating an APRI value. FIB-4 may better discriminate between intermediate fibrosis stages. Oct 25, 2021 · Background Liver biopsy is the gold standard for detecting the degree of liver fibrosis; however, invasiveness constitutes its main limiting factor in clinical application, so we aimed to evaluate the non-invasive biomarker formulas (APRI and FIB-4) and their modified forms by BMI z-score (M-APRI, M-FIB-4, and B-AST) compared to liver biopsy in the assessment of liver fibrosis in children with Oct 3, 2024 · APRIスコアを使用することには制限がありますか？はい、APRIスコアの信頼性は、急性肝臓の炎症や血小板数またはASTレベルに影響を与える他の病状によって影響される可能性があります。また、軽度の線維症段階の評価にはあまり有益ではありません。 What is FIB-4 or Apri? FIB-4 and APRI are both non-invasive tools used to assess liver fibrosis severity. Ofrece una alternativa a la biopsia hepática, que es más invasiva y conlleva un riesgo de complicaciones. FIB-4 y APRI, métodos no invasivos de predicción de la fibrosis hepática An APRI score calculator is available on CMCWEB under the Tools submenu and is available in the EHR under Guidelines. APRI Calculator The APRI Calculator is a non-invasive alternative to liver biopsy, designed to assess hepatic fibrosis and cirrhosis. 0 indeterminate; >1. Antecedentes históricos El índice APRI fue desarrollado como método más simple y menos riesgoso para The APRI (AST to Platelet Ratio Index) score is a non-invasive tool used to assess liver fibrosis severity. Oct 3, 2024 · APRI（丙氨酸转氨酶与血小板比值指数）评分是一种非侵入性工具，用于评估肝脏纤维化的程度，尤其针对丙型肝炎患者。它提供了一种替代肝脏活检的方法，后者更具侵入性，并且有并发症风险。历史背景 APRI 评分作为一种更简单、风险更低的方法而开发，用于评估肝纤维化和肝硬化。它易于计算 Create, share, and discover interactive calculators for any purpose. Using the APRI Calculator tool, enter in the patient's laboratory data and calculate the patient's APRI score. Using our APRI Calculator, medical professionals can easily and quickly calculate the APRI score, which is a non-invasive way to assess liver damage in patients with hepatitis C. How to Use the APRI Calculator: A Step-by-Step Guide Use the APRI calculator to assess the risk of liver fibrosis. Apri Calculator & other calculators Online calculators are a convenient and versatile tool for performing complex mathematical calculations without the need for physical calculators or specialized software. It provides an AST to Platelet Ratio Index (APRI) score using routine blood test parameters. Interpreting Your APRI Score Results ALBI and APRI demonstrated more accurate ability to predict PHLF than Child-Pugh and MELD. Oct 1, 2017 · The AST-to-Platelet Ratio Index (APRI) and fibrosis 4 calculator (FIB-4) score were originally designed for patients with chronic hepatitis C virus (HCV) infection, but several studies have demonstrated reasonable utility in assessing fibrosis in NAFLD patients, as well [9], [10]. Use the APRI calculator to assess the risk of liver fibrosis. It is calculated using the formula APRI = (AST / ULN) / PLT * 100, where AST is the Aspartate Aminotransferase level, ULN is the Upper Limit of Normal AST, and PLT is the platelet count. ️ Read on to discover the full interpretation of your results for both the FIB-4 index and the APRI score. Share Use the Child-Turcotte-Pugh Classification for Severity of Cirrhosis calculator to estimate the cirrhosis severity. AST is an enzyme that is typically Oct 1, 2024 · The APRI score helps detect liver fibrosis for people with liver disease. By analyzing the ratio of AST to the patient's platelet count, the APRI score offers a quick, cost-effective method to gauge fibrosis levels without requiring a liver biopsy Demystify the APRI score. The APRI score is a non-invasive index to predict the presence of liver fibrosis and cirrhosis, originally validated in patients with chronic hepatitis C. What is FIB-4 or Apri? FIB-4 and APRI are both non-invasive tools used to assess liver fibrosis severity. The NAFLD (Non-Alcoholic Fatty Liver Disease) Fibrosis Score estimates amount of scarring in the liver based on several laboratory tests. Enter AST, platelet count & reference value for a quick, noninvasive evaluation of liver health. Our study showed that APRI significantly correlates with CVR and determines, when elevated, a significant increase in CVR for both genders, especially females. Enter AST and platelet count to calculate the APRI score and see the likelihood of liver disease stages. Free medical calculator for healthcare professionals. Download Table | Utility of platelet count, AST/ALT ratio, and APRI score in predicting the presence of advanced fibrosis from publication: Clinical presentation, response to therapy, and The APRI score was calculated using the following formula: APRI score = [AST/upper limit of normal)/platelet count (10 9 /L)] ×100 (23). Oct 3, 2024 · L'utilisation du score APRI présente-t-elle des limites ? Oui, la fiabilité du score APRI peut être affectée par une inflammation hépatique aiguë et d'autres affections influant sur la numération plaquettaire ou les niveaux d'AST. Cutoffs vary by population/etiology. Although you can use the calculators Calculate the APRI Score to assess hepatic fibrosis risk. Calculate AST to Platelet Ratio Index (APRI), a non-invasive marker for liver fibrosis and cirrhosis. Calculating a patient's APRI score allows clinicians to easily predict hepatic fibrosis without performing a more invasive medical tests, e. The APRI score indicates the level of fibrosis in the liver, with higher scores indicating more severe fibrosis. Calculate the APRI score for hepatitis C-related fibrosis and cirrhosis using AST and platelet levels. The AST to Platelet Ratio Index (APRI) tool has been found to useful as a non-invasive index that correlates with liver biopsy findings of fibrosis and cirrhosis. Learn how to calculate the APRI score, interpret its results, and understand its role in diagnosing chronic liver disease. APRI or FIB-4 reduction did not correlate with fibrosis regression after 240 weeks of antiviral therapy. . Calculator: Aspartate aminotransferase (AST) to platelet ratio index (APRI) in adults (conventional units)* To continue reading this article, you must sign in with your personal, hospital, or group practice subscription. A PLR of three is considered clinically significant, and is interpreted as «the probability of a positive test (≥ APRI cutoff value) among the diseased (more fibrosis) is three times the probability of a positive test among the non-diseased (less fibrosis)». Jul 27, 2025 · A score <30 has a high negative predictive value, effectively ruling out steatosis, while a score >36 strongly suggests its presence. Enter AST, ULN, and platelet values to get instant screening results for chronic liver disease. The APRI score is a simple, inexpensive bedside marker that can detect liver fibrosis and cirrhosis. Find out more about what it is, how it’s calculated, and why doctors use it instead of biopsies. UpToDate UpToDate Using the APRI Calculator tool, enter in the patient's laboratory data and calculate the patient's APRI score. They calculate scores based on blood test results to estimate the degree of fibrosis in the liver. The APRI Score will appear in the oval on the far right (highlighted in yellow). Oct 3, 2024 · APRI（丙氨酸转氨酶与血小板比值指数）评分是一种非侵入性工具，用于评估肝脏纤维化的程度，尤其针对丙型肝炎患者。它提供了一种替代肝脏活检的方法，后者更具侵入性，并且有并发症风险。历史背景 APRI 评分作为一种更简单、风险更低的方法而开发，用于评估肝纤维化和肝硬化。它易于计算 Oct 3, 2024 · El índice APRI (relación entre AST y plaquetas) es una herramienta no invasiva que se usa para evaluar el grado de fibrosis hepática, particularmente en casos de hepatitis C. It uses two standard laboratory tests: the AST level and the platelet count. Fibrosis-4 (FIB-4) Calculator Share The Fibrosis-4 score helps to estimate the amount of scarring in the liver. Two online calculators that combined ALBI and APRI were proposed as useful preoperative and postoperative tools for individually predicting the occurrence of PHLF among patients with HCC. Why is APRI important? APRI is important because it provides a non-invasive method to estimate the level of liver fibrosis. This is a health tool that takes the AST score into account and the platelet count and delivers the APRI (AST to Platelet Ratio Index) score. Get an instant score and a detailed clinical interpretation on any device. Calculate the APRI Score to assess hepatic fibrosis risk. 5 for cirrhosis. Using the commonly-used 1. The higher this ratio, the better the diagnostic performance of the APRI score. The APRI Calculator takes these two values, does a bit of mathematical magic, and gives you a score that can help determine the extent of liver damage. 5 for fibrosis and 1. The APRI (AST to Platelet Ratio Index) formula is used to calculate the APRI score, which assesses liver fibrosis severity. Calculation of APRI. The APRI calculator computes the AST to Platelet Ratio Index (APRI), which we use to predict fibrosis and cirrhosis. The resulting number is your APRI score, offering a numerical representation derived from these common lab values. 5 into the high APRI group. APRI score measures the amount of fibrosis in the liver. Enter the required values to calculate the FIB-4 value. Select the applicable Clinical and Lab Criterias, then check the classification at the bottom. Jul 27, 2025 · Quickly assess liver fibrosis risk with our easy-to-use APRI Score Calculator. It helps medical professionals evaluate the potential presence of liver scarring, known as fibrosis. APRI and FIB-4 scores are easy to calculate using clinical parameters introduced in specific formulas, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), platelet count, and age. Initially validated for patients with chronic hepatitis C (CHC), the APRI is now widely used to evaluate other liver diseases. Enter the required values to calculate the APRI value. What is Apri? Apri is a brand of oral contraceptive that contains a combination of two hormones, desogestrel and ethinylestradiol. Related Activities You may find more information and a scenario for which you can use this calculator in the following activity from our curriculum: Calculating and Interpreting MELD Score This is an AST to Platelet Ratio Index calculator tool. 5–1. Answer the Activity Question based on the patient's APRI score. Learn the interpretation, sensitivity, specificity and sources of the APRI index. chronic hepatitis C): <0. Several studies have shown an association between APRI and NAFLD. Learn how to calculate this key liver health metric and understand what your numerical result truly means. A higher score correlates with a greater likelihood of significant fibrosis or cirrhosis. Apr 1, 2016 · APRI and FIB-4 scores at week 240 tended to be low and underestimate fibrosis stage in the patients with liver biopsies after 240 weeks of therapy. HSI predicts the presence of fat (steatosis), not scarring (fibrosis). It is calculated using the formula: [ (AST / Upper Limit of Normal AST) / Platelet Count (10^9/L)] × 100. APRI has been previously validated as an efficient score to predict liver fibrosis in viral hepatitis patients with a cut-off of 0. In the present study, we categorized APRI score ≤ 1. Aug 2, 2025 · To calculate, divide your AST level by the upper limit of the normal AST range, multiply by 100, and then divide by your platelet count (expressed as x 10^9/L). , biopsy. 0 suggests significant fibrosis; ≥2. Typically, a higher APRI score may indicate more advanced fibrosis. É melhor usá-la como parte de uma avaliação abrangente, considerando suas limitações e o contexto clínico específico. Aug 14, 2018 · Among them, the classic ones, including APRI and FIB-4 scores, have been recommended by the World Health Organization (WHO) guidelines for assessing hepatic fibrosis [5]. It offers a non-invasive way to predict which patients have cirrhosis without imaging or biopsy. APRI was calculated according to the formula proposed by Wai et al. To calculate APRI, serum AST activity and platelet count were used, both of which were obtained during the 15 days prior to the liver biopsy. Jul 25, 2025 · The APRI score calculator is a non-invasive tool used in healthcare to provide an initial assessment of liver health. Mar 25, 2025 · Explanation APRI Score Calculation Example: The APRI (AST to Platelet Ratio Index) score is a non-invasive marker used to assess the degree of liver fibrosis. The Fibrosis-4 (FIB-4) Index for Liver Fibrosis is a non-invasive scoring system based on several laboratory tests that help to estimate the amount of scarring in the liver. Non-Invasive Calculations to Predict Liver Damage APRI and FIB-4 Talk to your doctor about using non-invasive calculations such as AST to Platelet Ratio Index (APRI) and Fibrosis-4 index for Liver Fibrosis (FIB-4) to determine if there is evidence of liver disease. There are three fields in the calculator, the AST (aspartate aminotransferase) input in IU/L, the upper AST limit, set default at 40 IU/L but which can be modified according to need and the platelet count 109 Calculate APRI (AST to Platelet Ratio Index) for liver fibrosis assessment in chronic liver disease. APRI is a simple and no-cost method to estimate liver fibrosis and cirrhosis severity in patients with hepatitis C. Although you can use the calculators We would like to show you a description here but the site won’t allow us. By analyzing the ratio of AST to the patient's platelet count, the APRI score offers a quick, cost-effective method to gauge fibrosis levels without requiring a liver biopsy Apr 2, 2023 · The aspartate aminotransferase-to-platelet ratio index (APRI) and the fibrosis-4 (FIB-4) scores are two of these that are readily applicable. Thanks for taking the time to do this! Jul 1, 2021 · The APRI score was calculated using the following formula: APRI score = (AST/upper limit of normal)/platelet count [109 /L]) ×100 [25]. FIB 4 calculator will give fib 4 score for ruling out or confirming a diagnosis of advanced liver fibrosis risk. Calculators Please select a calculator on the right – it will display below. Perfect for financial planning, budgeting, investments, and more. Jul 21, 2025 · Use the APRI calculator to assess liver fibrosis or cirrhosis risk. APRI and FIB-4 scores are noninvasive markers for predicting the development of liver fibrosis in hepatitis C and nonalcoholic fatty liver disease (NAFLD) (11-13). g. Calculate APRI (AST to Platelet Ratio Index) for liver fibrosis assessment in chronic liver disease. ⬅️ We try our best to make our Omni Calculators as precise and reliable as possible. | Drlogy What is FIB-4 or Apri? FIB-4 and APRI are both non-invasive tools used to assess liver fibrosis severity.

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